Stability of an Extemporaneously Compounded Oral Suspension of Bosentan

Stability of Captopril in an Extemporaneously Compounded Humco’s Oral Products

Captopril oral suspensions were prepared by compounding Captopril powder with Humco’s Oral Products’ (Flavor Sweet : Flavor Plus 1:1; and Flavor Sweet-Sugar Free : Flavor Plus 1:1), at two concentrations: 0.8 mg/mL and 4 mg/mL. These bracket concentrations of all Captopril formulations were stored in low-actinic plastic prescription bottles at controlled room temperature (25 °C and 60% RH) and ...

Stability of gabapentin in extemporaneously compounded oral suspensions

This study reports the stability of extemporaneously prepared gabapentin oral suspensions prepared at 100 mg/mL from bulk drug and capsules in either Oral Mix or Oral Mix SF suspending vehicles. Suspensions were packaged in amber plastic bottles and amber plastic syringes at 25°C / 60%RH for up to 90 days. Throughout the study period, the following tests were performed to evaluate the stability...

Stability of Extemporaneously Compounded Amlodipine Besylate Oral Suspensions.

Stability of Diazoxide in Extemporaneously Compounded Oral Suspensions

The objective of this study was to evaluate the stability of diazoxide in extemporaneously compounded oral suspensions. Oral suspensions of diazoxide 10 mg/mL were prepared from either bulk drug or capsules dispersed in either Oral Mix or Oral Mix Sugar Free. These suspensions were stored at 5°C and 25°C/60%RH in bottles and oral syringes for a total of 90 days. At predetermined time intervals,...

Stability of propranolol in extemporaneously compounded suspensions.

BACKGROUND Propranolol is a drug of choice for many diseases occurring in neonates and infants, an age group for which oral suspensions are required almost exclusively. Many adult and elderly patients for whom propranolol is prescribed are also unable to swallow solid dosage forms. In Canada, propranolol is not commercially available in a liquid dosage form, and existing recipes for extemporane...